GIANT Genome-scale Integrated Analysis of gene Networks in Tissues
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Laboratory for Bioinformatics and Functional Genomics. In our research, we combine computational methods with an experimental component in a unified effort to develop comprehensive descriptions of genetic systems of cellular controls, including those whose malfunctioning becomes the basis of genetic disorders, such as cancer, and others whose failure might produce developmental defects in model systems. Understanding multicellular function and disease with human tissue-specific networks.
Measure the shadow; infer the bike. We bring together large compendia of publicly available data to answer pressing questions in biology and medicine. New technologies allow researchers to extensively profile biological systems, and researchers have embraced these technologies. Anyone can download more than 1. 9 million genome-wide assays from Array Express. Keep up with our latest papers, grants, and webservers.
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We revealed that giant.princeton.edu is weilding the Apache/2.2.15 (CentOS) operating system.HTML TITLE
GIANT Genome-scale Integrated Analysis of gene Networks in TissuesDESCRIPTION
My Gene Sets Tribe Login. Genome-scale Integrated Analysis of gene Networks in Tissues. Culture condition cd8 cell. Umbilical vein endothelial cell. Relevant tissues for query genes. GIANT leverages a tissue-specific gold standard to automatically up-weight datasets relevant to a tissue from a large data compendium of diverse tissues and cell-types. The resulting functional networks accurately capture tissue-specific functional interactions. Troyanskaya Laboratory - Princeton University.PARSED CONTENT
The web site had the following on the homepage, "Genome-scale Integrated Analysis of gene Networks in Tissues." We noticed that the web site said " Relevant tissues for query genes." It also said " GIANT leverages a tissue-specific gold standard to automatically up-weight datasets relevant to a tissue from a large data compendium of diverse tissues and cell-types. The resulting functional networks accurately capture tissue-specific functional interactions. Troyanskaya Laboratory - Princeton University."SEEK SIMILAR BUSINESSES
This server performs in silico nano-dissection, an approach we developed to identify genes with novel cell-lineage specific expression. This method leverages high-throughput functional genomics data from tissue homogenates to accurately predict genes enriched in specific cell types. Defining cell type specificity at the transcriptional level in human disease.
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This collection of tools is a subset of the tools, applications, and libraries developed within the Center for Quantitative Biology. They are provided here within a common framework, called the CQB Integrated Tools. Which allows for data to be processed and passed between them easily. The Integrated Tools framework also supports batch processing for multiple data sets natively within each tool and utilizes the local computing grid for high throughput.
What is a query? A query is a gene or a gene-set representing a biological theme that a user wants to investigate. Examples of a good query include genes from a common transcriptionally regulated pathway or process, a cellular component, a molecular complex, or a differentially expressed gene list or biomarker list. Start by entering a query, like GLI1 GLI2 PTCH1.
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